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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
21
hits in this display
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
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Affinity Data
IC50: 1.83E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
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Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.83E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.83E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.66E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.66E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.73E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.78E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.78E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.95E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compound
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.95E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compound
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.97E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.97E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.96E+3nM
Assay Description:
H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.16E+5nM
Assay Description:
Inhibitory activity against human GABA transporter-1 (hGAT1)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.16E+5nM
Assay Description:
Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 1
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.16E+5nM
Assay Description:
Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 2
(Rattus norvegicus)
Synaptic Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.63E+5nM
Assay Description:
Inhibitory activity against rat GABA transporter-2 (rGAT2)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 3
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.32E+6nM
Assay Description:
Inhibitory activity against human sodium and chloride dependent GABA transporter 3
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent GABA transporter 3
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.32E+6nM
Assay Description:
Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium- and chloride-dependent betaine transporter
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50020888
((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.41E+6nM
Assay Description:
Inhibition of human GABA transporter (hBGT-1) activity.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI