Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetAdenosine receptor A2b(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086185(3-[4-(1,3-Bis-cyclohexylmethyl-2,6-dioxo-2,3,6,7-t...)
Affinity DataKi:  199nMAssay Description:Antagonist activity against human A2B adenosine receptor expressed in HEK-293 cells uisng [3H]-ZM-241,385 or [125I]-IABOPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086185(3-[4-(1,3-Bis-cyclohexylmethyl-2,6-dioxo-2,3,6,7-t...)
Affinity DataKi:  602nMAssay Description:Antagonist activity against adenosine A1 receptor in rat brain membrane in presence of [3H]-R-PIA radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086185(3-[4-(1,3-Bis-cyclohexylmethyl-2,6-dioxo-2,3,6,7-t...)
Affinity DataKi:  922nMAssay Description:Antagonist activity against human adenosine A3 receptor expressed in HEK cells in presence of [125]IAB-MECA or [125I]-IABA radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086185(3-[4-(1,3-Bis-cyclohexylmethyl-2,6-dioxo-2,3,6,7-t...)
Affinity DataKi:  1.52E+3nMAssay Description:Antagonist activity against recombinant human adenosine A2A receptor expressed in HEK-293 cells in presence of [125I]-iodo-ZM241385 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086185(3-[4-(1,3-Bis-cyclohexylmethyl-2,6-dioxo-2,3,6,7-t...)
Affinity DataKi:  4.89E+3nMAssay Description:Antagonist activity against recombinant human adenosine A1 receptor expressed in HEK-293 cells in presence of [125I]-IABA radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed