Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetC-X-C motif chemokine 10(Homo sapiens (Human))
Sanofi

US Patent

LigandBDBM249591(US9447038, 19)Copy SMILESCopy InChI

Affinity DataIC50:  58nMT: 2°CAssay Description:The composition of the binding assay buffer is determined in a course of detailed optimization procedure. This resulted in a binding assay buffer con...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

LigandBDBM249591(US9447038, 19)Copy SMILESCopy InChI

Affinity DataIC50:  58nMAssay Description:Displacement of [125I]-CXCL10 from human recombinant CXCR3 transfected in Flp-In-CHO cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

LigandBDBM249591(US9447038, 19)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI