Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50127948((S)-3-(2-{5-Chloro-6-cyclopropyl-2-oxo-3-[(5,6,7,8...)Copy SMILESCopy InChI

Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against human alphaV-beta3 integrin using SPAV3 assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50127948((S)-3-(2-{5-Chloro-6-cyclopropyl-2-oxo-3-[(5,6,7,8...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+3nMAssay Description:Inhibitory activity against human alphaV-beta3 integrin using SPAV3 assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI