Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172461(1-(2',2''-Difluoro-4-hydroxy-[1,1';4',1'']terpheny...)
Affinity DataIC50:  3.36E+4nMAssay Description:Inhibitory concentration against beta-amyloid-42 (Abeta42) secretion was evaluated in human neuroglioma cells (H4-APP695NL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172461(1-(2',2''-Difluoro-4-hydroxy-[1,1';4',1'']terpheny...)
Affinity DataIC50:  5.80E+4nMAssay Description:Interaction with human cytochrome P450 isoform 3A4 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172461(1-(2',2''-Difluoro-4-hydroxy-[1,1';4',1'']terpheny...)
Affinity DataIC50:  7.40E+4nMAssay Description:Interaction with human cytochrome P450 isoform 2C19 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172461(1-(2',2''-Difluoro-4-hydroxy-[1,1';4',1'']terpheny...)
Affinity DataIC50:  1.11E+5nMAssay Description:Concentration required to inhibit A beta 40 peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed