Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172459(1-(2-Fluoro-4''-hydroxy-[1,1';4',1'']terphenyl-4-y...)
Affinity DataIC50:  2.15E+4nMAssay Description:Interaction with human cytochrome P450 isoform 2D6 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172459(1-(2-Fluoro-4''-hydroxy-[1,1';4',1'']terphenyl-4-y...)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibitory concentration against beta-amyloid-42 (Abeta42) secretion was evaluated in human neuroglioma cells (H4-APP695NL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172459(1-(2-Fluoro-4''-hydroxy-[1,1';4',1'']terphenyl-4-y...)
Affinity DataIC50:  3.50E+4nMAssay Description:Interaction with human cytochrome P450 isoform 2C19 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172459(1-(2-Fluoro-4''-hydroxy-[1,1';4',1'']terphenyl-4-y...)
Affinity DataIC50:  8.90E+4nMAssay Description:Interaction with human cytochrome P450 isoform 2C9 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172459(1-(2-Fluoro-4''-hydroxy-[1,1';4',1'']terphenyl-4-y...)
Affinity DataIC50:  4.09E+5nMAssay Description:Concentration required to inhibit A beta 40 peptide 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed