Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039253(1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piper...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039253(1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piper...)
Affinity DataIC50:  1.27E+6nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039253(1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piper...)
Affinity DataIC50:  3.67E+6nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039253(1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piper...)
Affinity DataIC50:  6.74E+6nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed