Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Solute carrier family 22 member 2
(RAT)
Institute Of Anatomy Of The Bayerische Julius-Maximilians-Universit£T
Curated by
ChEMBL
Ligand
BDBM50303766
(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.00E+5nM
Assay Description:
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Solute carrier family 22 member 1
(RAT)
Institute Of Anatomy Of The Bayerische Julius-Maximilians-Universit£T
Curated by
ChEMBL
Ligand
BDBM50303766
(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.40E+5nM
Assay Description:
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Zhengzhou University
Curated by
ChEMBL
Ligand
BDBM50303766
(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.00E+5nM
Assay Description:
Inhibition of KDM5B (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50303766
(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.00E+3nM
Assay Description:
Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 298K temperature in presence of HIF1alpha (55...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50303766
(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 900nM
Assay Description:
Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by 1H-15N HSQC titration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50303766
(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 900nM
Assay Description:
Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 298K temperature
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50303766
(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.20E+3nM
Assay Description:
Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 313K temperature
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50303766
(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.70E+3nM
Assay Description:
Binding affinity to human PHD2-Mn(II) using 100% H2O MQC spectrometer operated at 23 MHz at 313K temperature
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50303766
(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 900nM
Assay Description:
Binding affinity to human PHD2 by nondenaturing ESI-MS
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI