Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandBDBM214743(Rhodanines, 31A)Copy SMILESCopy InChI

Affinity DataIC50:  650nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchasePC cidPC sid

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TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine

Curated by ChEMBL

LigandBDBM50431330(CHEMBL2348832)Copy SMILESCopy InChI

Affinity DataIC50:  750nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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