Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine

Curated by ChEMBL

LigandBDBM8436(2-[(5Z)-5-(furan-2-ylmethylidene)-4-oxo-2-sulfanyl...)Copy SMILESCopy InChI

Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandBDBM8436(2-[(5Z)-5-(furan-2-ylmethylidene)-4-oxo-2-sulfanyl...)Copy SMILESCopy InChI

Affinity DataIC50:  1.40E+5nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI