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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Macrophage migration inhibitory factor
(Homo sapiens (Human))
Yale University
Curated by
ChEMBL
Ligand
BDBM50206062
(CHEMBL3890541 | US10968198, Example 44)
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Affinity Data
Ki: 37nM
Assay Description:
Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Macrophage migration inhibitory factor
(Homo sapiens (Human))
Yale University
Curated by
ChEMBL
Ligand
BDBM50206062
(CHEMBL3890541 | US10968198, Example 44)
Copy SMILES
Copy InChI
Affinity Data
Ki: 37nM
Assay Description:
Inhibition of recombinant human MIF tautomerase activity using 4-hydroxyphenyl pyruvic acid (HPP) as substrate pre-incubated for 30 mins and followed...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Macrophage migration inhibitory factor
(Homo sapiens (Human))
Yale University
Curated by
ChEMBL
Ligand
BDBM50206062
(CHEMBL3890541 | US10968198, Example 44)
Copy SMILES
Copy InChI
Affinity Data
Ki: 45nM
Assay Description:
Data obtained for the Example compounds, obtained using the methods described in Example B.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI