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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM16238
(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)
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Affinity Data
IC50: 30nM
Assay Description:
Inhibition of human ALR2
More data for this Ligand-Target Pair
Target Info
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3D Structure (crystal)
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Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM16238
(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
pH: 7.0
Assay Description:
The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM16238
(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
pH: 7.0 T: 2°C
Assay Description:
The assays were performed at 25 degrees Celsius in a 100mM sodium phosphate buffer (pH 7.0), with the AR protein amount reaching the Vmax and 0.2mM N...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B10
(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Ligand
BDBM16238
(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)
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Copy InChI
Affinity Data
IC50: 2.70E+3nM
pH: 7.0
Assay Description:
The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B10 [K125R,V301L]
(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Ligand
BDBM16238
(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.40E+3nM
pH: 7.0
Assay Description:
The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B10
(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Ligand
BDBM16238
(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.40E+3nM
pH: 7.0
Assay Description:
The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI