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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
University Of Michigan Medical School
Curated by
ChEMBL
Ligand
BDBM53262
(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
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Affinity Data
Ki: 820nM
Assay Description:
Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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Target
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM53262
(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
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Affinity Data
Ki: 2.30E+3nM
Assay Description:
Displacement of 1,8-ANS from His6-tagged FABP4 (unknown origin) expressed in Escherichia coli BL21(DE3) cells by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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antibodypedia
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Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
University Of Michigan Medical School
Curated by
ChEMBL
Ligand
BDBM53262
(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
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Affinity Data
IC50: 2.70E+3nM
Assay Description:
Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal b...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Hexokinase HKDC1 [W721R]
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM53262
(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
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Affinity Data
IC50: 4.67E+3nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
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Target
Methyl-CpG-binding domain protein 2
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM53262
(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
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Affinity Data
IC50: 4.87E+3nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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Target
Hexokinase HKDC1 [W721R]
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM53262
(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.67E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
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Target
Zinc finger protein mex-5
(Caenorhabditis elegans)
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM53262
(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
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Affinity Data
EC50: 6.30E+3nM
Assay Description:
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...
More data for this Ligand-Target Pair
Target Info
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Target
POsterior Segregation
(Caenorhabditis elegans)
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM53262
(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
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Affinity Data
EC50: 3.68E+4nM
Assay Description:
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/TrEMBL
GoogleScholar
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Target
Nuclear factor erythroid 2-related factor 2
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM53262
(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
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Affinity Data
Kd: 1.53E+4nM
Assay Description:
Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as compound's equilibrium dissociation constant after 60 mins by fluorescence anisotro...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
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Article
PubMed
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