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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
University Of Michigan Medical School
Curated by
ChEMBL
Ligand
BDBM50013865
(CHEMBL3265297)
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Affinity Data
Ki: 170nM
Assay Description:
Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Bcl-2-related protein A1
(Homo sapiens (Human))
University Of Michigan Medical School
Curated by
ChEMBL
Ligand
BDBM50013865
(CHEMBL3265297)
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Affinity Data
Ki: 1.11E+3nM
Assay Description:
Displacement of Flu-BID/FAM-BID from His-tagged A1-BFL-1 (1 to 151) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluoresce...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bcl-2-like protein 2
(Homo sapiens (Human))
University Of Michigan Medical School
Curated by
ChEMBL
Ligand
BDBM50013865
(CHEMBL3265297)
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Affinity Data
Ki: 1.36E+3nM
Assay Description:
Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Apoptosis regulator Bcl-2
(Homo sapiens (Human))
University Of Michigan Medical School
Curated by
ChEMBL
Ligand
BDBM50013865
(CHEMBL3265297)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.11E+3nM
Assay Description:
Displacement of Flu-BID/FAM-BID from His-tagged BCL2 (1 to 202) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bcl-2-like protein 1
(Homo sapiens (Human))
University Of Michigan Medical School
Curated by
ChEMBL
Ligand
BDBM50013865
(CHEMBL3265297)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.59E+3nM
Assay Description:
Displacement of Flu-BID/FAM-BID from His-tagged BCLX-L (1 to 209) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
University Of Michigan Medical School
Curated by
ChEMBL
Ligand
BDBM50013865
(CHEMBL3265297)
Copy SMILES
Copy InChI
Affinity Data
IC50: 880nM
Assay Description:
Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal b...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI