Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL

LigandBDBM50363059(CHEMBL1946964)Copy SMILESCopy InChI

Affinity DataIC50:  850nMAssay Description:Inhibition of recombinant N-His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using pyridine-3-aldehyde as substrate by spectrophotometryMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL

LigandBDBM50363059(CHEMBL1946964)Copy SMILESCopy InChI

Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human recombinant AKR1B1 expressed in Escherichia coli BL21 cells using pyridine-3-aldehyde as substrate by spectrophotometryMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAldo-keto reductase family 1 member A1(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL

LigandBDBM50363059(CHEMBL1946964)Copy SMILESCopy InChI

Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant AKR1A1 expressed in Escherichia coli BL21 cells using D-glucuronate as substrate by spectrophotometryMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI