Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent

LigandBDBM214702(US9296728, 25)Copy SMILESCopy InChI

Affinity DataIC50:  48nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent

LigandBDBM214702(US9296728, 25)Copy SMILESCopy InChI

Affinity DataIC50:  90nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI