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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
1
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Target
DNA-(apurinic or apyrimidinic site) endonuclease
(Homo sapiens (Human))
University Of Southern California
Ligand
BDBM26580
(4-({4-[(4-carboxyphenyl)sulfanyl]benzene}sulfonyl)...)
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Affinity Data
IC50: 4.00E+3nM
pH: 7.5 T: 2°C
Assay Description:
To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...
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