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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human))
University Of Modena And R.E.
Curated by
ChEMBL
Ligand
BDBM50257478
(2-(4'-Hydroxyphenyl)-3-[(4''carboxy-3''-hydroxy-1,...)
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Affinity Data
IC50: 700nM
Assay Description:
Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human))
University Of Modena And R.E.
Curated by
ChEMBL
Ligand
BDBM50257478
(2-(4'-Hydroxyphenyl)-3-[(4''carboxy-3''-hydroxy-1,...)
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Copy InChI
Affinity Data
IC50: 900nM
Assay Description:
Inhibition of human cloned PTP1B expressed in Escherichia coli TB1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human))
University Of Modena And R.E.
Curated by
ChEMBL
Ligand
BDBM50257478
(2-(4'-Hydroxyphenyl)-3-[(4''carboxy-3''-hydroxy-1,...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.70E+3nM
Assay Description:
Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI