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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
(Homo sapiens (Human))
Tes Pharma
US Patent
Ligand
BDBM261588
(US10513499, Compound 11 | US11254644, Compound 11 ...)
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Affinity Data
IC50: 71nM
Assay Description:
The pre-assay mixture consisting of 3-hydroxyanthranilic acid (3OH-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
(Homo sapiens (Human))
Tes Pharma
US Patent
Ligand
BDBM261588
(US10513499, Compound 11 | US11254644, Compound 11 ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 71nM
Assay Description:
The activity of compounds 1-19 and 21-23 as inhibitors of ACMSD1 was determined by measuring the conversion of 3OH-Anthranilic Acid into product (i.e...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
(Homo sapiens (Human))
Tes Pharma
US Patent
Ligand
BDBM261588
(US10513499, Compound 11 | US11254644, Compound 11 ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 71nM
Assay Description:
The pre-assay mixture consisting of 3-hydroxyanthranilic acid (30H-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
(Homo sapiens (Human))
Tes Pharma
US Patent
Ligand
BDBM261588
(US10513499, Compound 11 | US11254644, Compound 11 ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 99nM
Assay Description:
Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI