Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50020919(CHEMBL3287282)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBcl-2-like protein 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50020919(CHEMBL3287282)Copy SMILESCopy InChI

Affinity DataIC50:  21nMAssay Description:Inhibition of GST-tagged Bcl-xL (unknown origin) measured after 1 hr incubation by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50020919(CHEMBL3287282)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at Bcl-2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI