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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Beta-lactamase
(Aeromonas hydrophila)
Universit£
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
Ki: 5.70E+3nM
Assay Description:
Inhibition of Aeromonas hydrophila beta lactamase CphA by competitive inhibition assay
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Target
Beta-lactamase
(Aeromonas hydrophila)
Universit£
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
Ki: 4.60E+4nM
Assay Description:
Inhibition of Aeromonas hydrophila beta lactamase CphA at pH 7.0
More data for this Ligand-Target Pair
Target Info
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Article
PubMed
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Target
Beta-lactamase
(Aeromonas hydrophila)
Universit£
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
Ki: 7.60E+4nM
Assay Description:
Inhibition of Aeromonas hydrophila beta lactamase CphA at pH 8.0
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
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ChEBI
CHEMBL
KEGG
MMDB
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Article
PubMed
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Target
Beta-lactamase
(Aeromonas hydrophila)
Universit£
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
Ki: 4.40E+5nM
Assay Description:
Inhibition of Aeromonas hydrophila beta lactamase CphA at pH 9.0
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
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ChEBI
CHEMBL
KEGG
MMDB
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In Depth
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Article
PubMed
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Target
Beta-lactamase
(Aeromonas hydrophila)
Universit£
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
Copy SMILES
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Affinity Data
Ki: 1.10E+6nM
Assay Description:
Inhibition of Aeromonas hydrophila beta lactamase CphA at pH 10.0
More data for this Ligand-Target Pair
Target Info
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Target
Proton-coupled amino acid transporter 1
(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
Ki: 1.80E+7nM
Assay Description:
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting
Checked by Author
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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Target
Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
IC50: 1.00E+5nM
Assay Description:
Inhibition of prolyl 4-hydroxylase
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Target
Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
IC50: 1.12E+5nM
Assay Description:
Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna
More data for this Ligand-Target Pair
Target Info
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Target
Putative dihydropicolinate synthase
(Streptomyces coelicolor)
TBA
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
IC50: 1.00E+6nM
Assay Description:
In vitro inhibibition of dihydrodipicolinic acid synthase.
More data for this Ligand-Target Pair
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Target
Beta-lactamase
(Klebsiella pneumoniae)
Uit The Arctic University Of Norway
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
IC50: >2.00E+6nM
Assay Description:
Inhibition of native signal containing Klebsiella pneumoniae OXA-48 using nitrocefin substrate pre-incubated for 5 mins before substrate addition
More data for this Ligand-Target Pair
Target Info
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ChEBI
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Target
Beta-lactamase
(Klebsiella pneumoniae)
Uit The Arctic University Of Norway
Curated by
ChEMBL
Ligand
BDBM50000407
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
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Affinity Data
Kd: >1.00E+6nM
Assay Description:
Binding affinity to native signal deficient and TEV cleavage site containing His-tagged Klebsiella pneumoniae OXA-48 expressed in Escherichia coli as...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
KEGG
MMDB
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI