Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL

LigandBDBM50072093(CHEMBL3407875)Copy SMILESCopy InChI

Affinity DataIC50:  90nMAssay Description:Inhibition of human KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL

LigandBDBM50072093(CHEMBL3407875)Copy SMILESCopy InChI

Affinity DataIC50:  90nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL

LigandBDBM50072093(CHEMBL3407875)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human KMO transfected in CHO cells assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI