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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Lysine-specific demethylase 4C
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50153340
(CHEMBL3775245)
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Affinity Data
IC50: 316nM
Assay Description:
Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...
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Target Info
PDB
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Target
Lysine-specific demethylase 4D
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50153340
(CHEMBL3775245)
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Affinity Data
IC50: 398nM
Assay Description:
Inhibition of human KDM4D (11 to 341 residues) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectromet...
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Target Info
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Target
Prolyl hydroxylase EGLN3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50153340
(CHEMBL3775245)
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Affinity Data
IC50: 3.16E+4nM
Assay Description:
Inhibition of full length His-MBP-att-EGLN3 (1 to 239 residues) (unknown origin) in Escherichia coli BL21(DE3)pRR692 cells assessed as hydroxylation ...
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Target Info
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Target
Lysine-specific demethylase 6B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50153340
(CHEMBL3775245)
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Affinity Data
IC50: 3.98E+4nM
Assay Description:
Inhibition of human KDM6B catalytic domain using H3(20 to 36 residues)K27Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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