Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

US Patent

LigandBDBM209110(US9266877, 56)Copy SMILESCopy InChI

Affinity DataKi:  24nM ΔG°:  -43.5kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetBcl-2-like protein 1(Mus musculus (Mouse))
Abbvie

US Patent

LigandBDBM209110(US9266877, 56)Copy SMILESCopy InChI

Affinity DataEC50:  583nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI