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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
1
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Target
DNA-(apurinic or apyrimidinic site) endonuclease
(Homo sapiens (Human))
University Of Southern California
Ligand
BDBM26609
(3-[(pyridin-2-ylsulfanyl)methyl]-1-benzofuran-2-ca...)
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Affinity Data
IC50: 2.70E+4nM
Assay Description:
To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...
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