Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50066851(CHEMBL3401640)Copy SMILESCopy InChI

Affinity DataIC50:  6.10nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHOK1 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50066851(CHEMBL3401640)Copy SMILESCopy InChI

Affinity DataIC50:  15nMAssay Description:Displacement of [3H]NMS from human M3 receptor expressed in CHOK1 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50066851(CHEMBL3401640)Copy SMILESCopy InChI

Affinity DataIC50:  35nMAssay Description:Displacement of [3H]NMS from human M2 receptor expressed in CHOK1 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI