Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Carbonic anhydrase 4
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50159798
(CHEMBL182856 | Sodium; L-Malate)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.37E+4nM
Assay Description:
Binding affinity against human cytosolic Carbonic anhydrase IV
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase
(Candida albicans (Yeast))
Università
Curated by
ChEMBL
Ligand
BDBM50257204
(CHEMBL493556 | sodium (S)-2-hydroxysuccinate)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.77E+4nM
Assay Description:
Inhibition of Candida albicans Nce103
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase [110-330]
(Flaveria bidentis (Coastal plain yellowtops))
Istituto Di Biostrutture E Bioimmagini-Cnr
Ligand
BDBM50159798
(CHEMBL182856 | Sodium; L-Malate)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.25E+4nM ΔG°: -22.6kJ/mole
pH: 8.3 T: 2°C
Assay Description:
Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C.
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50159798
(CHEMBL182856 | Sodium; L-Malate)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.87E+6nM
Assay Description:
Binding affinity against human cytosolic Carbonic anhydrase II
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50257204
(CHEMBL493556 | sodium (S)-2-hydroxysuccinate)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.87E+6nM
Assay Description:
Inhibition of human carbonic anhydrase2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50159798
(CHEMBL182856 | Sodium; L-Malate)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.49E+6nM
Assay Description:
Binding affinity against human cytosolic Carbonic anhydrase V
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50159798
(CHEMBL182856 | Sodium; L-Malate)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.42E+6nM
Assay Description:
Binding affinity against human cytosolic Carbonic anhydrase IX
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-ketoglutarate-dependent dioxygenase FTO
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM92495
(Malate)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl 4-hydroxylase
(Paramecium bursaria Chlorella virus 1)
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50510127
(CHEBI:30797 | CHEMBL1234046)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Methyl-accepting chemotaxis protein NahY
(Pseudomonas putida (Arthrobacter siderocapsulatus))
Csic
Ligand
BDBM92495
(Malate)
Copy SMILES
Copy InChI
Affinity Data
Kd: 8.50E+3nM
T: 2°C
Assay Description:
Measurements were done on a VP-microcalorimeter (MicroCal, Amherst, MA).
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI