Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118324(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-8-yl)pipe...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118324(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-8-yl)pipe...)
Affinity DataKi:  24nMAssay Description:Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade Federal Da Para£Ba

Curated by ChEMBL
LigandPNGBDBM50118324(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-8-yl)pipe...)
Affinity DataKi:  550nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118324(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-8-yl)pipe...)
Affinity DataIC50:  18.0nMAssay Description:Inhibition of (+)-8-OH-DPAT stimulated [35S]-GTP-gammaS, binding to 5-hydroxytryptamine 1A receptor in hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed