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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50220586
(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
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Affinity Data
IC50: 6.80nM
Assay Description:
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50220586
(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50220586
(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50220730
((R)-6-(2-(4-(3-fluorophenyl)-4-hydroxypiperidin-1-...)
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Affinity Data
IC50: 1.10E+3nM
Assay Description:
Displacement of [3H]dofetilide from human HERG expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50220586
(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.80E+3nM
Assay Description:
Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50220586
(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10E+4nM
Assay Description:
Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50220586
(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10E+4nM
Assay Description:
Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI