Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304947(6-(4-benzoylpiperidin-1-yl)-N-(2-hydroxy-2-phenyle...)
Affinity DataIC50:  108nMAssay Description:Inhibition of human Scd1 expressed in HEK-293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304947(6-(4-benzoylpiperidin-1-yl)-N-(2-hydroxy-2-phenyle...)
Affinity DataIC50:  153nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304947(6-(4-benzoylpiperidin-1-yl)-N-(2-hydroxy-2-phenyle...)
Affinity DataIC50:  292nMAssay Description:Inhibition of Scd1 in human HEK-293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed