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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Aldehyde dehydrogenase, mitochondrial
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM118201
(US8673966, N-(4-(7-((1-hydroxycyclopentyl)ethynyl)...)
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Affinity Data
IC50: 386nM
pH: 7.4
Assay Description:
Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM118201
(US8673966, N-(4-(7-((1-hydroxycyclopentyl)ethynyl)...)
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Affinity Data
IC50: >1.30E+5nM
pH: 7.5
Assay Description:
MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with esterase. Standard MAO reacti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Amine oxidase [flavin-containing] A
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM118201
(US8673966, N-(4-(7-((1-hydroxycyclopentyl)ethynyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.30E+5nM
pH: 7.5
Assay Description:
MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with esterase. Standard MAO reacti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI