Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetE3 ubiquitin-protein ligase Mdm2 [1-118,T47W](Homo sapiens (Human))
Jagiellonian University

LigandPNGBDBM207986(3-(4-Chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-5-(4...)
Affinity DataKd:  2.87E+4nMpH: 7.4 T: 2°CAssay Description:MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2 [1-118](Homo sapiens (Human))
Jagiellonian University

LigandPNGBDBM207986(3-(4-Chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-5-(4...)
Affinity DataKd:  1.80E+4nMpH: 7.4 T: 2°CAssay Description:Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed