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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
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Target
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human))
Industry-Academic Cooperation Foundation, Chosun University
US Patent
Ligand
BDBM50347949
(CHEMBL599406 | US8637558, 46)
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Affinity Data
IC50: 50.9nM
pH: 7.5
Assay Description:
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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US Patent
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Target
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human))
Industry-Academic Cooperation Foundation, Chosun University
US Patent
Ligand
BDBM50347949
(CHEMBL599406 | US8637558, 46)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human))
Industry-Academic Cooperation Foundation, Chosun University
US Patent
Ligand
BDBM50347949
(CHEMBL599406 | US8637558, 46)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of PGDH (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human))
Industry-Academic Cooperation Foundation, Chosun University
US Patent
Ligand
BDBM50347949
(CHEMBL599406 | US8637558, 46)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of human GST-fused 15-PGDH expressed in Escherichia coli BL21 using PGE2 as substrate assessed as formation of NADH by fluorescence spectr...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human))
Industry-Academic Cooperation Foundation, Chosun University
US Patent
Ligand
BDBM50347949
(CHEMBL599406 | US8637558, 46)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI