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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human))
Chungbuk National University
Curated by
ChEMBL
Ligand
BDBM50438424
(CHEMBL2414139 | US8637558, 17)
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Affinity Data
IC50: 223nM
Assay Description:
Inhibition of human GST-fused 15-PGDH expressed in Escherichia coli BL21 using PGE2 as substrate assessed as formation of NADH by fluorescence spectr...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human))
Chungbuk National University
Curated by
ChEMBL
Ligand
BDBM50438424
(CHEMBL2414139 | US8637558, 17)
Copy SMILES
Copy InChI
Affinity Data
IC50: 308nM
pH: 7.5
Assay Description:
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI