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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022415(6-chloro-(4'S)-spiro[3,4-dihydro-2H-chromene-4,5'-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022398((+)-6-chloro-2,3-dihydro-2'H,4'H-spiro[chromene-4,...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity towards partially purified calf lens aldose reductase; value ranges from 10E-6 - 10E-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022398((+)-6-chloro-2,3-dihydro-2'H,4'H-spiro[chromene-4,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration was determined against partially purified calf lens aldose reductase using glyceraldehyde as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022398((+)-6-chloro-2,3-dihydro-2'H,4'H-spiro[chromene-4,...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration was determined against partially purified calf lens aldose reductase using glyceraldehyde as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022411(6-chloro-(4'R)-spiro[3,4-dihydro-2H-chromene-4,5'-...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of partially purified calf lens aldose reductase; value ranges from 10E-4 to 10e-5 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022398((+)-6-chloro-2,3-dihydro-2'H,4'H-spiro[chromene-4,...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibitory concentration was determined against partially purified calf lens aldose reductase using glyceraldehyde as a substrate; 10e-4/10e-5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed