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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Glycogen phosphorylase, liver form
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM35346
((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
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Affinity Data
IC50: 205nM
Assay Description:
In vitro inhibitory activity against recombinant human liver glycogen phosphorylase a (rHLGPa) catalyzed release of phosphate from glucose-1-phosphat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
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Target
Glycogen phosphorylase, muscle form
(Homo sapiens (Human))
Novo Nordisk
Curated by
ChEMBL
Ligand
BDBM35346
((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
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Affinity Data
IC50: 500nM
Assay Description:
Inhibition of Rabbit muscle glycogen phosphorylase B.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Glycogen phosphorylase, liver form
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM35346
((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
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Copy InChI
Affinity Data
IC50: 920nM
pH: 6.8 T: 2°C
Assay Description:
The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycogen phosphorylase, liver form
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM35346
((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 920nM
pH: 6.8 T: 2°C
Assay Description:
The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycogen phosphorylase, liver form
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM35346
((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40E+3nM
Assay Description:
In vitro inhibition of pig liver Glycogen phosphorylase A.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lanosterol 14-alpha demethylase
(Homo sapiens (Human))
Act
Curated by
ChEMBL
Ligand
BDBM35346
((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
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Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI