Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetHormone-sensitive lipase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50224152(4-hydroxy-piperidine-1-carboxylic acid 4-(5-triflu...)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant human HSL expressed in Sf9 insect cells using PNPB as substrate measured after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50224152(4-hydroxy-piperidine-1-carboxylic acid 4-(5-triflu...)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224152(4-hydroxy-piperidine-1-carboxylic acid 4-(5-triflu...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of acetylcholine esteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224152(4-hydroxy-piperidine-1-carboxylic acid 4-(5-triflu...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of butyrylcholine esteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed