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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Integrin alpha-V/beta-8
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
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Affinity Data
IC50: 0.400nM
pH: 7.4 T: 2°C
Assay Description:
Recombinant human LAP protein (R&D Systems, Inc, 246-LP) diluted to 0.5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM C...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-5/beta-6
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.400nM
Assay Description:
Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-V/beta-5
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.400nM
Assay Description:
Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-V/beta-8
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.400nM
Assay Description:
Recombinant human LAP protein (R&D Systems, Inc, 246-LP) diluted to 0.5 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-V/beta-6
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.400nM
pH: 7.4 T: 2°C
Assay Description:
Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-V/beta-5
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.400nM
pH: 7.4 T: 2°C
Assay Description:
Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-5/alpha-8
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.600nM
Assay Description:
Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-8/beta-1
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.600nM
pH: 7.4 T: 2°C
Assay Description:
Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-5/beta-1 [T112H]
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.700nM
Assay Description:
Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-5/beta-1
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.700nM
pH: 7.4 T: 2°C
Assay Description:
Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-5/alpha-V
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-V/beta-1
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
pH: 7.4 T: 2°C
Assay Description:
Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Recombinant human vitronectin (R& D Systems, 2308-VN) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2,...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Saint Louis University
US Patent
Ligand
BDBM279563
((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
pH: 7.4 T: 2°C
Assay Description:
Recombinant human vitronectin (R& D Systems, 2308-VN) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2,...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI