Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W]
(Homo sapiens (Human))
Jagiellonian University
Ligand
BDBM207982
(N-(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)- 3-(...)
Copy SMILES
Affinity Data
Kd: 2.44E+4nM
pH: 7.4 T: 2°C
Assay Description:
MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
E3 ubiquitin-protein ligase Mdm2 [1-118]
(Homo sapiens (Human))
Jagiellonian University
Ligand
BDBM207982
(N-(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)- 3-(...)
Copy SMILES
Affinity Data
Kd: 1.64E+5nM
pH: 7.4 T: 2°C
Assay Description:
Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI