Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Aventis Pharmaceuticals

LigandBDBM84445(Isoindoline, 12)Copy SMILESCopy InChI

Affinity DataKi:  0.5nMAssay Description:Dopamine D4.2 and D2S receptor binding was performed at NPS Allexlix Corp.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetD(2) dopamine receptor(Homo sapiens (Human))
Aventis Pharmaceuticals

LigandBDBM84445(Isoindoline, 12)Copy SMILESCopy InChI

Affinity DataKi:  55.9nMAssay Description:Dopamine D4.2 and D2S receptor binding was performed at NPS Allexlix Corp.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Aventis Pharmaceuticals

LigandBDBM84445(Isoindoline, 12)Copy SMILESCopy InChI

Affinity DataKi:  232nMAssay Description:All rat alpha-1 adrenoceptor binding was performed by Hugo M. vargas, Karen M. Brooks and Lynn Laws-Ricker.More data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI