Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50185471(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-(2-hydroxyethyl)...)Copy SMILESCopy InChI

Affinity DataIC50:  1nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50185471(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-(2-hydroxyethyl)...)Copy SMILESCopy InChI

Affinity DataIC50:  25.9nMAssay Description:Inhibition of alphavbeta6 integrin in HT29 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI