Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNeutrophil elastase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50279771(CHEMBL217744 | [4-Benzyloxy-5-{5-benzyloxy-4-[5-be...)Copy SMILESCopy InChI

Affinity DataKi:  130nMAssay Description:Inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetProthrombin(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50279771(CHEMBL217744 | [4-Benzyloxy-5-{5-benzyloxy-4-[5-be...)Copy SMILESCopy InChI

Affinity DataKi:  750nMpH: 7.5Assay Description:Inhibition of thrombin at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Bz-Phe-Val-Arg-pNA.More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetCathepsin G(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50279771(CHEMBL217744 | [4-Benzyloxy-5-{5-benzyloxy-4-[5-be...)Copy SMILESCopy InChI

Affinity DataKi: >1.50E+4nMpH: 7.5Assay Description:Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI