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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity measured at the 5-hydroxytryptamine 2A receptor by the inhibition of [3H]-ketanserin binding to rat cortex using unlabeled mianserin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity measured at the Alpha-1A adrenergic receptor by the inhibition of [3H]-prazosin binding to rat cortex using unlabeled WB-4101 for no...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity measured at the Dopamine receptor D3 by the inhibition of [3H]-YM-09151-2 binding to human recombinant CCL 1.3 cells using unlabeled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  12nMAssay Description:Binding affinity measured at the Dopamine receptor D2 by the inhibition of [3H]-methylspiperone binding to rat striatum using unlabeled haloperidol f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  94nMAssay Description:Binding affinity measured at the 5-hydroxytryptamine 1A receptor by the inhibition of [3H]-8-OH-DPAT binding to rat cortex using unlabeled buspirone ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  179nMAssay Description:Binding affinity measured at the Dopamine receptor D4 by the inhibition of [3H]-spiperone binding to human recombinant CHO cells using unlabeled halo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  239nMAssay Description:Binding affinity measured at the Dopamine receptor D1 by the inhibition of [3H]-SCH-23,390 binding to rat striatum using unlabeled apomorphine for no...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  490nMAssay Description:Binding affinity measured at the sigma receptor by the inhibition of [3H]-3-PPP binding to guinea pig cerebellum using unlabeled 3-PPP for nonspecifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of [3H]-ketanserin binding to rat frontal cortex membrane 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer

Curated by ChEMBL
LigandPNGBDBM50072822(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataIC50:  17nMAssay Description:Inhibition of [3H]-methylspiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed