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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 1.90nM
Assay Description:
Binding affinity measured at the 5-hydroxytryptamine 2A receptor by the inhibition of [3H]-ketanserin binding to rat cortex using unlabeled mianserin...
More data for this Ligand-Target Pair
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Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 2.40nM
Assay Description:
Binding affinity measured at the Alpha-1A adrenergic receptor by the inhibition of [3H]-prazosin binding to rat cortex using unlabeled WB-4101 for no...
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 5.40nM
Assay Description:
Binding affinity measured at the Dopamine receptor D3 by the inhibition of [3H]-YM-09151-2 binding to human recombinant CCL 1.3 cells using unlabeled...
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Target Info
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 12nM
Assay Description:
Binding affinity measured at the Dopamine receptor D2 by the inhibition of [3H]-methylspiperone binding to rat striatum using unlabeled haloperidol f...
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 94nM
Assay Description:
Binding affinity measured at the 5-hydroxytryptamine 1A receptor by the inhibition of [3H]-8-OH-DPAT binding to rat cortex using unlabeled buspirone ...
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Target Info
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Target
D(4) dopamine receptor
(Homo sapiens (Human))
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 179nM
Assay Description:
Binding affinity measured at the Dopamine receptor D4 by the inhibition of [3H]-spiperone binding to human recombinant CHO cells using unlabeled halo...
More data for this Ligand-Target Pair
Target Info
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Target
D(1A) dopamine receptor
(RAT)
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 239nM
Assay Description:
Binding affinity measured at the Dopamine receptor D1 by the inhibition of [3H]-SCH-23,390 binding to rat striatum using unlabeled apomorphine for no...
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 490nM
Assay Description:
Binding affinity measured at the sigma receptor by the inhibition of [3H]-3-PPP binding to guinea pig cerebellum using unlabeled 3-PPP for nonspecifi...
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Target Info
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Copy SMILES
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Affinity Data
IC50: 6.20nM
Assay Description:
Inhibition of [3H]-ketanserin binding to rat frontal cortex membrane 5-hydroxytryptamine 2A receptor
More data for this Ligand-Target Pair
Target Info
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PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Centro De InvestigacióN Grupo Ferrer
Curated by
ChEMBL
Ligand
BDBM50072822
(7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Copy SMILES
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Affinity Data
IC50: 17nM
Assay Description:
Inhibition of [3H]-methylspiperone binding to rat striatal membrane Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
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