Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50113024((2R,4S)-1-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]...)Copy SMILESCopy InChI

Affinity DataIC50:  14nMAssay Description:Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50113024((2R,4S)-1-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]...)Copy SMILESCopy InChI

Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI