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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(CHEMBL445717 | benzyl 5-(2-((3RS,5S,6S)-5-(hydroxy...)
Affinity DataIC50:  137nMAssay Description:Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50268904(CHEMBL445717 | benzyl 5-(2-((3RS,5S,6S)-5-(hydroxy...)
Affinity DataIC50:  302nMAssay Description:Inhibition of human recombinant ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(CHEMBL445717 | benzyl 5-(2-((3RS,5S,6S)-5-(hydroxy...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(CHEMBL445717 | benzyl 5-(2-((3RS,5S,6S)-5-(hydroxy...)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(CHEMBL445717 | benzyl 5-(2-((3RS,5S,6S)-5-(hydroxy...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(CHEMBL445717 | benzyl 5-(2-((3RS,5S,6S)-5-(hydroxy...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed