Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

LigandPNGBDBM50228001((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of HER2 sheddase in BT474 cells by extracellular domain shedding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228001((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
Affinity DataIC50:  37nMAssay Description:Binding affinity to ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228001((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
Affinity DataIC50:  106nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228001((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
Affinity DataIC50:  2.62E+3nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228001((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228001((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed