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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Disintegrin and metalloproteinase domain-containing protein 10
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50228001
((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
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Affinity Data
IC50: 26nM
Assay Description:
Inhibition of HER2 sheddase in BT474 cells by extracellular domain shedding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
Disintegrin and metalloproteinase domain-containing protein 10
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50228001
((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 37nM
Assay Description:
Binding affinity to ADAM10
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50228001
((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
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Copy InChI
Affinity Data
IC50: 106nM
Assay Description:
Binding affinity to MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50228001
((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
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Affinity Data
IC50: 2.62E+3nM
Assay Description:
Binding affinity to MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50228001
((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
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Copy InChI
Affinity Data
IC50: 4.00E+3nM
Assay Description:
Binding affinity to MMP3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50228001
((6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperazine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
Binding affinity to MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI