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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50268953
((1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl...)
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Affinity Data
IC50: 180nM
Assay Description:
Inhibition of human MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50268953
((1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl...)
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Affinity Data
IC50: 470nM
Assay Description:
Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 10
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50268953
((1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl...)
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Affinity Data
IC50: 1.55E+3nM
Assay Description:
Inhibition of human recombinant ADAM10
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Interstitial collagenase
(Homo sapiens (Human))
Incyte
Curated by
ChEMBL
Ligand
BDBM50268953
((1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl...)
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Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of human MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI