Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50320391(CHEMBL1083932 | N-hydroxy-4-(4-(4-phenylpiperidin-...)Copy SMILESCopy InChI

Affinity DataIC50:  4.40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50320391(CHEMBL1083932 | N-hydroxy-4-(4-(4-phenylpiperidin-...)Copy SMILESCopy InChI

Affinity DataIC50:  6nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50320391(CHEMBL1083932 | N-hydroxy-4-(4-(4-phenylpiperidin-...)Copy SMILESCopy InChI

Affinity DataIC50:  265nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50320391(CHEMBL1083932 | N-hydroxy-4-(4-(4-phenylpiperidin-...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI