Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50:  44nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50:  76nMAssay Description:Inhibition of HER2 sheddase in human BT474 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50:  100nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50:  135nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50:  942nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed