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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
1
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Target
Bifunctional purine biosynthesis protein ATIC
(Homo sapiens (Human))
The Scripps Research Institute
Ligand
BDBM22584
(5-bromo-2-[9-chloro-3-(sulfooxy)naphtho[1,2-b]thio...)
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Affinity Data
IC50: 1.40E+3nM
pH: 7.5 T: 2°C
Assay Description:
The human ATIC enzyme was used for the inhibition assay. The assay buffer was flushed with nitrogen to minimize oxidization of cofactor 10-f-THF. The...
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Article
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